Christopher E. Miles

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• arXiv
• bioRxiv

1. 2026
   1. Efficient approximate Bayesian inference for large, heterogeneous biological datasets

      JT Zanussi, CE Miles

      preprint
   2. Identifiability Limits of Physics-Informed Inference for Spatial Stochastic Dynamics from Static Snapshots

      R Gu, RZ Zhang, CE Miles

      preprint
   3. Reconstructing Actin Dynamics of the Leading Edge from Observational Data

      W Shi, CE Miles, J Noh, G Danuser, A Mogilner

      PNAS
   4. The kinetochore corona orchestrates chromosome congression through transient microtubule interactions

      CE Miles, F Renda, I Tikhonenko, A Alfieri, A Mogilner, A Khodjakov

      PNAS
   5. BiLO: Bilevel Local Operator Learning for PDE Inverse Problems

      RZ Zhang, CE Miles, X Xie, JS Lowengrub

      J Comp Phys
   6. Bayesian BiLO: Bilevel Local Operator Learning for Efficient Uncertainty Quantification of Bayesian PDE Inverse Problems with Low-Rank Adaptation

      RZ Zhang, CE Miles, X Xie, JS Lowengrub

      Nat Commun
   7. Variational Markov chain mixtures with automatic component selection

      CE Miles, RJ Webber

      Stat Comput
2. 2025
   1. Scalable inference and identifiability of kinetic parameters for transcriptional bursting from single cell data

      J Gu, N Laszik, CE Miles, J Allard, TL Downing, EL Read

      Bioinformatics
   2. Mechanistic inference of stochastic gene expression from structured single-cell data (review)

      CE Miles

      Curr Opin Sys Bio
   3. Revisiting Murray's Law in Pulmonary Arteries: Exploring Branching Patterns and Principles

      SA Correa, A Kachabi, M Colebank, CE Miles, N Chelser

      J Biomech Eng
   4. Incorporating spatial diffusion into bursty stochastic models of transcription

      CE Miles

      J R Soc Interface
   5. Computational modeling reveals a catch-and-guide interaction between kinesin-1 and tubulin C-terminal tails

      T Nguyen, SP Gross, CE Miles

      Traffic
3. 2024
   1. Coaching ribosome biogenesis from the nuclear periphery

      Y Zhuang, X Guo, OV Razorenova, CE Miles, W Zhao, X Shi

      preprint
   2. Inferring stochastic rates from heterogeneous snapshots of particle positions

      CE Miles, SA McKinley, F Ding, RB Lehoucq

      Bull Math Bio
   3. Competition between physical search and a weak-to-strong transition rate-limits kinesin binding times

      T Nguyen, BJN Reddy, SP Gross, CE Miles

      PLoS Comp Bio
   4. Intrinsic statistical separation of subpopulations in heterogeneous collective motion via dimensionality reduction

      P Tan, CE Miles

      Phys Rev E
4. 2023
   1. Mathematicians Convene at 2023 Southern California Applied Mathematics Symposium (SoCAMS)

      M Aminian, K Kurianski, A Ma, CE Milesnews report

      SIAM News
   2. Stochastic switching of delayed feedback suppresses oscillations in genetic regulatory systems

      BR Karamched, CE Miles

      J R Soc Interface
   3. Coarse-grained dynamics of transiently-bound fast linkers

      S Marbach, CE Miles

      J Chem Phys
5. 2022
   1. Mechano-sensing in actin networks: capping it off for robustness

      CE Miles, A Mogilnerdispatch

      Curr Biol
   2. Non-centrosomal microtubules at kinetochores promote rapid chromosome biorientation during mitosis in human cells

      F Renda, CE Miles, …, A Mogilner, A Khodjakov

      Curr Biol
   3. Mechanical torque promotes bipolarity of the mitotic spindle

      CE Miles, J Zhu, A Mogilner

      Bull Math Bio
6. 2021
   1. Collective Molecular Motor Transport

      CE Miles, A Mogilnerbook chapter

      Case Stud Sys Bio
7. 2020
   1. Effects of malleable kinetochore morphology on measurements of intrakinetochore tension

      F Renda, …, CE Miles, A Mogilner, A Khodjakov

      Open Biology
   2. Actin-Membrane Release Initiates Cell Protrusions

      ES Welf, CE Miles, …, A Mogilner, G Danuser

      Dev Cell
   3. Receptor organization shapes the limits of single-cell direction sensing

      SD Lawley, AE Lindsay, CE Miles

      Phys Rev Lett
8. 2019
   1. Diffusive search for diffusing targets with fluctuating diffusivity and reactivity

      SD Lawley, CE Miles

      J Nonlinear Sci
   2. Complex nearly immotile behavior of microtubule-associated cargos

      O Osunbayo, CE Miles, BJ Reddy, JP Keener, MD Vershinin

      Soft Matter
   3. How receptor surface diffusion and cell rotation enhance association rates

      SD Lawley, CE Miles

      SIAM J Appl Math
9. 2018
   1. Analysis of non-processive molecular motor transport using renewal reward theory

      CE Miles, SD Lawley, JP Keener

      SIAM J Appl Math
10. 2017
    1. Jump locations of jump-diffusion processes with state-dependent rates

       CE Miles, JP Keener

       J Phys A
    2. Bidirectionality from cargo thermal fluctuations in motor-mediated transport

       CE Miles, JP Keener

       J Theor Bio

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Team

Tim Tian

Postdoc · Utah Math

plant cortical microtubules, geometry + stochastic modeling

fav veggie: napa cabbage 🥬

Jacy Zanussi

PhD Student · UCI MCSB

methods for simulation-based inference (co-advised w/ John Lowengrub)

fav veggie: all peppers 🌶️ honorary

Austin Marcus

PhD Student · UCI MCSB

nuclear condensates, cilia (co-advised w/ Jun Allard)

fav veggie: onion 🧅

Rebecca (Rujie) Gu

PhD Student · UCI Math

physics-informed neural networks + point processes

fav veggie: spinach 🍃

Matt Lastner

PhD Student · Utah Math Bio

meiosis biophysics, polymer models (co-advised w/ Ofer Rog)

fav veggie: sweet potato 🍠

🥦

You?

Prospective students: apply to Utah Math and/or reach out to Chris.

fav veggie: be ready to defend it

Alumni (10)

Trini Nguyen

MCSB PhD 2024 (co-advised w/ Steve Gross)

after: Postdoc, Cedars-Sinai Hospital

fav veggie: bittermelon 🥒

Pei Tan

MCSB MS 2023

after: Bioinformatics Specialist, UCI Med.

fav veggie: any appetizer 🥘

Christopher Au

2024 MathExpLR high school student

fav veggie: tomato 🍅 honorary

Dhara Hansalia

2024 MathExpLR high school student

fav veggie: cucumber 🥒

Luca Valdevit

2024 MathExpLR high school student

fav veggie: potato 🥔

Aditya Radhakrishnan

2023 MathBioU undergrad

fav veggie: cauliflower

Masha Gorodetski

2023 MathExpLR high school student

fav veggie: carrots 🥕

Junyi (Claire) Li

2022 MathExpLR high school student

fav veggie: potatoes 🥔

Tanya Vidhun

2022 MathExpLR high school student

fav veggie: spinach 🥗

David Militante

2022 MathBioU undergrad

fav veggie: carrots 🥕

Chris Miles

PI · Utah Math

fav veggie: beet 🫜

fav animal: binturongSay hi to Mee-noi & Berani at the Living Planet Aquarium in Draper. Finn (left) + Piper (right) + a foster (middle) fav movie: In the Mood for Love

Hobbies: skiing when it snows, gaming when it doesn't (mostly the case, lately).

Not to be confused with: Chris Miles (rapper), Christopher J. Miles (other mathematician), or Chris Miles (artist).

1. 2013BS ECE, BS MathLafayette College
2. 2018PhD MathematicsUniversity of Utahadvisor: Jim Keener
3. 2018–21Courant InstructorCourant Institute, NYUmentor: Alex Mogilner
4. 2021–25Assistant ProfessorUC Irvine
5. 2025–nowAssociate ProfessorUniversity of Utah

• Bulletin of Mathematical BiologyEditorial Board · since 2024
• PLOS Computational BiologyAcademic Editor · since 2025